This paper presents a new and structured approach to address uncertainty and sensitivity analysis in Life Cycle Assessment (LCA) to support the decision-making process in building renovation. This “probabilistic” approach to LCA allows for the obtaining of results expressed as ranges of environmental impacts and for alternative solutions, offering an idea of the meaning of input parameters’ uncertainties and their influence on the result. The methodology application is illustrated through a case study where three building retrofit measures were assessed. Results provide an insight about the uncertainties of LCA indicators in terms of climate change and non-renewable energy.

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